Golnaz Mahmoudvand; Hamze Ali Torang; Arian Karimi Rouzbahani
Abstract
Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves multiple organs. Pregnant women previously diagnosed with SLE are at risk of experiencing gestational complications. However, cases of initial SLE manifestation during pregnancy are rare.Case Presentation: ...
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Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves multiple organs. Pregnant women previously diagnosed with SLE are at risk of experiencing gestational complications. However, cases of initial SLE manifestation during pregnancy are rare.Case Presentation: A 45-year-old pregnant woman (G7P2Ab4) was admitted to Shahid Rahimi Hospital in Khorramabad, Iran, in the 29th week of gestation due to thrombocytopenia. The patient had received a diagnosis of SLE during a routine prenatal visit but had not responded to the prescribed medications. After a comprehensive clinical and paraclinical evaluation, the patient was treated with pulse intravenous methylprednisolone, followed by prednisolone, dramatically improving her clinical condition.Conclusion: Diagnosing and managing SLE during pregnancy can be controversial. An accurate evaluation of the patient’s clinical condition is essential for determining the most effective treatment strategy. A multidisciplinary approach is necessary to ensure the best possible outcomes for the mother and the fetus.
Soheila Akbari; Arian Karimi Rouzbahani; Masoumeh Ghaffarzadeh; Golnaz Mahmoudvand; Leila Fathi; Shaghayegh Mapar; Parsa Namdari; Fatemeh Yari
Abstract
Background: Vitamin D deficiency/insufficiency can be regarded as a crucial public health obstacle that affects about 50% of the world’s population. Pregnant women are at a relatively high risk of developing deficient concentrations of vitamin D, which can result in detrimental pregnancy outcomes. ...
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Background: Vitamin D deficiency/insufficiency can be regarded as a crucial public health obstacle that affects about 50% of the world’s population. Pregnant women are at a relatively high risk of developing deficient concentrations of vitamin D, which can result in detrimental pregnancy outcomes. This survey was designed to evaluate the correlation between serum vitamin D concentrations and first-trimester spontaneous abortion.Methods: This was a case-control study conducted at the Asalian Referral Gynecological Hospital in Khorramabad, Iran, from April 2021 to March 2022. Forty-two women hospitalized due to spontaneous pregnancy loss in the first trimester were recruited as cases, and 100 individuals referred for routine pregnancy care constituted the control group. Demographic and clinical data were recorded for all subjects, and blood samples were taken from both groups to determine serum vitamin D levels. The data were recorded on a researcher-made checklist. The chi-squared test and logistic regression were used for analysis in SPSS version 22.Results: The frequency of vitamin D deficiency/insufficiency was higher in the case group (n=10, 23.8%) than in the control group (n=21, 21%), although this difference was not significant (P=0.899). Logistic regression revealed a significant link between vitamin D deficiency/insufficiency and age (P<0.001), gestational age (P=0.005), and body mass index (P<0.001).Conclusion: The results suggested no significant association between vitamin D deficiency/insufficiency and miscarriage during the first trimester.
